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francois.delmotte@inrae.fr

Parcours

• Since 2023. Associate director of Institut des Sciences de la Vigne et du Vin (ISVV)
• Since 2018. Head of UMR 1065 SAVE (staff 70 persons) 
• Since 2014. Research Director INRAE, SAVE, Bordeaux, France
• Since 2003. Research Scientist INRAE, Santé et Agroécologie du Vignoble (SAVE), Bordeaux, France 
• 2001-2002 - Marie Curie Fellowship, Instituto Cavanilles Biodiversidad y Biología Evolutiva, Univ Valencia, Spain / Andres Moya
• PhD Thesis, INRAE Rennes, France / Jean-Christophe Simon 

Scientific expertise 

• Associate editor (2022present) Oeno-One ; (2011-2023) European Journal of Plant Pathology
• Scientific expert (2012-2013) at the French National Agency for Food, Environmental Health and Safety
• CST Institut Français de la Vigne et du Vin, CST du Bureau National Interprofessional du Cognac
• International conference committees: Int. Conf. Grapevine Breeding & Genetics, Grapevine Powdery & Downy Mildew Int. Workshop, International Symposium on Phylloxera

Thématiques de recherche

My research aims to uncover the processes that generate genome variation and to understand how these processes shape microbial adaptation. Our team focuses on Plasmopara viticola, the grapevine downy mildew pathogen, which is engaged in a co-evolutionary arms race with its hosts. We use population genomics approaches to study diversity across populations at different environmental scales. Recently, we described the first genetic determinants (avirulence genes) that drive P. viticola interactions with grapevine, and we characterize the diversity and evolution of effectors mediating pathogen-host interactions. This knowledge contributes to the sustainable management of plant genetic resistance. 
The second goal of my research is to integrate evolutionary and ecological perspective into the management of plant diseases. Population genetics provides a theoretical framework for designing strategies that limit the emergence and spread of genotypes with major agronomic impact. My aim is therefore to generate knowledge and develop tools that support sustainable, agroecological strategies for vineyard protection. This includes innovative preventive management approaches based on the diruption of the pathogen’s sexual cycle.

Recent projects 

• Coordination ANR Vitae , PPR Cultiver Protéger Autrement, 3 M€, 2021-2027.
• Coordination Chaire Alexis Millardet , Fondation Université de Bordeaux 
• Co-coordination PARSADA Savoir , 4 M€, Ministère de l’Agriculture et de la Souveraineté Alimentaire (MASA), 2025-2029.